Pemphigus complex

The Pemphigus canines and felines represent approximately 0.3% of cutaneous processes. Affect middle-aged animals, no predilection of these processes has been found by one sex but if race: Akita, Chow chow, dachshund, Newfoundland, Bearded collie, German Shepherd and Doberman pinscher in Pemphigus Erythematosus Pemphigus Foliaceus, and German Shepherd and Collie. Also described a greater appearance of Bullous Pemphigoid in Doberman pinscher and Collie

What is the cause and how?

It is a autoimmune disease (see explanation in Lupus). The Pemphigus complex is characterized by the appearance of vesicle-blistering lesions that evolve pustules may also appear to ulcerative erosive lesions surrounded by epidermal collaretes to break the vesicles or pustules. These lesions appear at the level of the skin but they are also of interest to the mucous membranes. Vesicles and pustules are impermanent then there is occurrence in the crustyellowish s process.The various processes of Pemphigus manifested differences with respect to the location of the lesions.

Pemphigus complex

* Pemphigus Vulgaris
*Pemphigus Foliaceus: the distribution of the lesions are usually on the face and generally very scaly.
* Pemphigus Erythematosus. Injury to the face type of photosensitisation and nonpigmented nose considered as a benign form of the Foliaceus or as a hybrid between lupus erythematosus and Pemphigus Foliaceus.
* Pemphigus Vegetans: lesions that resemble papillomas (verrugiformes), it is extremely rare.
* Bullous Impetigo:Affect the mouth, skin, and other unions Mucocutaneous: lips, ollares, eyelids, foreskin, vulva, year.

In any of these diseaseis autoimmune the presence of itching and pain is variable depending on the case, may also be a general symptomatology in the animal as a decreased appetite or persistent fever.

In the case of the diseaseis cowperś the diagnosis is made by biopsy of the affected tissue (requires the exploration of the animal every few hours to find emerging vesicles).

Is it serious?

The prognosis of the disease varies with the form and intensity of the process. Thus, Pemphigus Vulgaris is fatal in 95% of untreated cases, progressive weakness and generalized infections but with very good results (rather than cure but if improvement) in case of establishing a treatment and to respond to the safatal without treatmentme. Pemphigus Foliaceus It is less severe, with a good prognosis if it is but also can be fatal without treatment. The Erythematosus Pemphigus Vegetans and are considered benign forms without affectation general taking better prognosis.

Does cure?
No cure but if treatment. The control of autoimmune processes affecting the skin requires the administration of large amounts of glucocorticoids via systemic, with or without the administration of any other drug inmunodepresora. In addition the secondary complications of each case must combat in particular.

The treatment is generally combined with antibiotics oral or injectable and shampoos Keratolytic bathrooms.

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