Indications of radiotherapy

Currently, veterinarians have new tools for the treatment of the cancer of our patients. Surgery and chemotherapy can add, external radiotherapy. Since the first use of radiation for the treatment of tumors in animals (Richard Eberlein, 1906) until today, radiation therapy plays an important role in local treatment of tumors.

Radiation and surgery are local treatments, i.e., its function is the treat to the tumor and its margins. For both therapies, previously defined a field of treatment, and that is where the therapeutic action is exercised.

Defined the target of treatment, ionizing radiation acting on the tissues in two ways: direct and indirect. The mechanism of direct action done on DNA, while the indirect phenomenon is through the formation of radical free, with oxygen and water from the tissuewhite s.

Indications of radiotherapy

Canines and cats, radiotherapy indicates tumors:

1. Of head and neck
2. With incomplete exceresis
3. Of cellround s

1.- Tumors located in the region of the head and neck, are a frequent and extensive group of pathology Oncology s. In relation to the radiosensibles of the head and neck tumors, can be grouped in the following neoplasias: • Brain: meningioma and pituitary • Nasal cavity • Oral cavity • Oropharyngeal • Larynx • Neoplasm skin s of the region: “s squalors cell carcinoma- canine and feline”

2.- On occasions, after the surgery, the margins histopathological analysis is positive. This indicates that an unknown number of cell tumor s is in the operated region and the likelihood of relapse is high. To do this, we can complement surgical treatment with radiation on the tumor bed. After the healing of the wound can radiate field adjuvant. purposes

3.- S round cell tumors are highly radiosensibles. This group is composed of the following tumors: • Lymphoma • Mastocytoma • Histiocytoma • Transmissible Venereal tumor or Sticker (TVT).

The sensitivity of these features allows a rapid reduction of tumor volumes. This allows, for example, the emergency treatment for lymphoma. In cases of severe respiratory distress, the irradiation of the affected linfonodular region, provides an adequate and speedy relief to the signs.

In another cell round s, as the TVT tumor, the high radio sensitivities makes it possible to “cure” the tumor (100% complete response) with a single implementation of 10 total Gy. To the TVT so it is considered unique in its kind, and is the subject of study within the tumor radiobiology in mammals.

In conclusion, we must discuss side effects of radiation are local, that is defined in the field of treatment. These unwanted effects correlate with the type of plan used and defined by the veterinary radiation.

The variables are as follows: the dose per fraction (DPF), the total dose of the treatment (DTT) and the total time of treatment (TTT). No major side effects, still superficial inflammatory reactions which can be observed more frequently are noted in the planning of routine.

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